Transplantation Science Committee Awards

The Transplantation Science Committee (TSC) of The Transplantation Society (TTS) will award the first two new prestigious annual prizes to the best basic science and translational science papers published in Transplantation.

The TSC is extremely pleased that Professors Leslie B. Brent and Anthony P. Monaco have agreed to have these awards named in their honor.

Leslie B. Brent Award

for the most outstanding paper published in Transplantation in the field of Basic Science research

Anthony P. Monaco Award

for the most outstanding paper published in Transplantation in the field of Translational Science research

Previous Winners

• 2018

  Winners to be annouced at ITS 2019 which is being held from Nov. 10-13 in Clearwater Beach, Florida.

• 2017

  Leslie B. Brent Award

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  for the most outstanding paper published in Transplantation in the field of Basic Science research

  Drs. Duran-Struuck and Sondermeijer

  “Effect of Ex Vivo-Expanded Recipient Regulatory T Cells on Hematopoietic Chimerism and Kidney Allograft Tolerance Across MHC Barriers in Cynomolgus Macaque”
  Transplantation.

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  Anthony P. Monaco Award

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  for the most outstanding paper published in Transplantation in the field of Translational Science research

  Dr. Martens

  ““Humoral Reactivity of Renal Transplant-Waitlisted Patients to Cells from GGTA1/CMAH/B4GalNT2, and SLA Class I Knockout Pigs”
  Transplantation.

• 2016

  Leslie B. Brent Award

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  for the most outstanding paper published in Transplantation in the field of Basic Science research

  Dr. Takemoto

  “Coaggregates of Regulatory T Cells and Islet Cells Allow Long-term Graft Survival in Liver Without Immunosuppression”
  Transplantation. 99(5):942-947, May 2015.

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  Anthony P. Monaco Award

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  for the most outstanding paper published in Transplantation in the field of Translational Science research

  Dr. Lucas

  “Differences in Immunogenicity of HLA Antigens and the Impact of Cross-Reactivity on the Humoral Response.”
  Transplantation. 99(1):77-85, January 2015.

• 2014

  Leslie B. Brent Award

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  for the most outstanding paper published in Transplantation in the field of Basic Science research

  Irene Kim

  Cedars-Sinai Medical Center, United States
  “Anti-Interleukin 6 Receptor Antibodies Attenuate Antibody Recall Responses in a Mouse Model of Allosensitization”
  Transplantation. 2014 Dec 27;98(12):1262-70

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  Anthony P. Monaco Award

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  for the most outstanding paper published in Transplantation in the field of Translational Science research

  Eytan Breman

  Celyad S.A., Belgium
  “HLA Monomers as a Tool to Monitor Indirect Allorecognition”
  Transplantation. 2014 Jun 15;97(11):1119-27.

TTS Young Investigator Awards

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. Select a year to view recipient details:

The recipients of the TTS Young Investigator Scientific Awards submitted abstracts to the 2018 Congress and received the highest scores from an international panel of reviewers. Rebeca Arroyo Hornero, United Kingdom Co-Stimulatory Modulation of Human Regulatory T cells for Enhanced Immunotherapy Yarl Balachandran, United States Delineation of the Viral and Host Cell Genomic Alterations in EBV-positive PTLD Florencia Bonisconti, Argentina Clinical Utility of a Modified qRT-PCR for Trypa- nosoma Cruzi Detection in Transplant Patients Xiaoyong Chen, People's Republic of China Characterization of a CD23+CD43+ Regulatory B Cell Subset in Human that Induced by Mesenchymal Stem Cells Aravind Cherukuri, United States Prospective Multicenter Validation of Human Transitional B cell Cytokines as a Predictive Biomarker in Renal Transplantation Fang Kuan Chiou, Singapore Poorer Long-Term Survival Associated with Monomorphic Post-Transplant Lymphoproliferative Disorder After Solid Organ Transplantation in Children Dominik Chittka United States DSA plus TCMR Leads to Poor Outcomes in Renal Allograft Recipients and this is Markedly Exacerbated by Non-Adherence Helong Dai, People's Republic of China Distal Abdominal Aorta Could Serve as an Out-flow Tract for en Bloc Kidney Transplantation from Infant Donors with Extremely Low Body Weight Nicole De La Mata, Australia Stroke Mortality in Kidney Transplant Recipients: A Retrospective Population-Based Cohort Study using Data Linkage Reinier de Vries, United States Extending the Human Liver Preservation Time for Transplantation by Supercooling Su Kah Goh, Australia Donor-Specific Cell-Free DNA as an Emerging Biomarker of Organ Rejection after Liver Transplantation Christian Heim, Germany Blockade of Tyrosine Kinases as Preventive Strategy Against Cardiac Allograft Vasculopathy in a Murine Aortic Transplant Model Charlotte Lee, United Kingdom The Anti-Inflammatory Effect of Alpha-1 Antitrypsin in Hepatocyte Transplantation Xiaoqian Ma, People's Republic of China Cord Blood Derived Regulatory Macrophages (Mreg) – An Alternative Source for Mreg-based Cell Therapy in Transplantation Berenice Mbiribindi, United States NK Cell Recognition of Peptides Encoded by EBV Latent Cycle Proteins Hiroyuki Ogasawara, Japan A Comparison of the Transplant Efficiency between Intraportal and Intrasplenic Procedures in Hepatocyte Transplantation Brenda Rosales, Australia Cancer Mortality in Transplant Recipients in Australia and New Zealand: A National Cohort Study from 1980 to 2013 Akhil Sharma, United States Pro-inflammatory B Cells Predict Progressive Minimal Early Renal Allograft Inflammation Which Is Associated With Poor Graft Outcomes Nicole Shockcor, United States End Stage Renal Disease as a Complication of Face Transplant Ashley Suah, United States Acquired Resistance to Transplantation Tolerance as a Result of Prior Pregnancy Requires B Cells Patrick Trotter, United Kingdom Transplantation of Kidneys from DCD and DBD Donors who Died after Ligature Asphyxiation: the UK Experience Marieke van der Zwan, The Netherlands Efficacy of Rabbit Anti-Thymocyte Globulin Therapy for Severe Acute Rejection in Kidney Transplant Patients using Calcineurin Inhibitor and Mycophenolate Mofetil based ImmunosuppressiveTherapy Karen Waller, Australia Incidence, Prevalence and Residual Infection Risk of HIV in Increased Risk Groups Presenting as Potential Organ Donors in Australia; A Systematic Review and Meta-Analysis Casey Ward, United States Reversal of Diabetes and Preservation of Pancreatic Islet Grafts in the Extrahepatic Space with Novel Parathyroid Gland Co-Transplantation Cheng Yang, People's Republic of China Prediction of Renal Allograft Chronic Rejection using a Model Based on Contrast Enhanced Ultrasonography Yuanfei Zhao, Australia In-vivo Costimulation-Blockade induced Foxp3 Tregs from DEREG Mice with Neonatal Islet Cell Cluster Tolerant Xenografts Exist Memory Tregs Phenotype

PENELOPE ALLEN, Australia The impact of recurrent glomerulonephritis after kidney transplantation in the era of contemporary maintenance immunosuppression VAISHNAVI CALISA, Australia The relative costs and health benefits of an age-matched deceased donor allocation algorithm compared to current practice ARAVIND CHERUKURI, United States Early de novo DSA with T Cell Mediated Rejection (TCMR) is Associated with Allograft Dysfunction with Chronic Injury JASON DAVIS, Unites States Changes in liver allograft steatosis and its impact on early graft function and long term survival DENIS EFIMOV, Belarus DAMP-associated preservation injury and complications after liver transplantation: proof of concept SHAIMAA ELKHOLY, Egypt Predictors of Mortality In Living Donor Liver Transplantation JIANING FU, United States Generation of naïve donor-derived lymphocytes from graft-resident lymphoid progenitors after human intestinal transplantation BARBARA KERN, Australia, Nonalcoholic Steatohepatitis as Indication for Liver Transplantation in Europe. Clinical Analysis of over 37.000 Patients QIANG LIU, United States Triglyceride exportation in the preservation of discarded steatotic human livers using 24 hours ex-vivo normothermic machine perfusion DAVID NASRALLA, Unites Kingdom A Multicentre Randomised Controlled Trial to Compare the Efficacy of Normothermic Machine Perfusion with Static Cold Storage in Human Liver Transplantation: Early Outcomes KEVIN TAK-PAN NG, Hong Kong Up-regulation of GSTA2 at early-phase after liver transplantation increases the risk of late-phase hepatocellular carcinoma recurrence THOMAS SCHACHTNER, Germany Kinetics of CMV-specific T-cells From Pre-to-Posttransplantation Predict Outcomes in CMV-seronegative Kidney Transplant Recipients OSCAR SERRANO, United States Defining the tipping point in surgical performance in laparoscopic donor nephrectomy during abdominal transplant surgery fellowship: a learning curve analysis. RASHMI SHINGDE, Australia Trojan Kidneys: Unexpected Donor-Derived Viral Transmission in Kidney Transplant Recipients – a Systematic Review UMANG THAKKAR, India Stem cell therapy as an emerging modality for post-traumatic paraplegia and for renal parenchymal diseases MIRJAM TIELEN, Netherlands Importance of Early Medication Adherence for Long-Term Graft Survival: A Prospective, Single-Centre Cohort Study THOMAS VANHOVE, Belgium Tubulointerstitial expression of connective tissue growth factor in renal allograft protocol biopsies at 3 months predicts interstitial fibrosis at 5 years GEORGIOS VRAKAS, United Kingdom De Novo Donor-Specific HLA Antibodies after Combined Intestinal and Vascularized Composite Allotransplantation JOHANNES WEDEL, United States DEPTOR modulates alloimmunity by increasing regulatory T cell function and stabilizing Foxp3 expression CHENG YANG, China Cyclic Helix B Peptide Inhibits Ischemia Reperfusion-induced Renal Fibrosis via the PI3K/Akt/FoxO3a Pathway WAI HO OSCAR YEUNG, Hong Kong Dysregulation of transforming growth factor beta receptor III induces tumor promoting macrophages via complement C3a in Hepatocellular Carcinoma recurrence after liver transplantation

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc. Deyaa El Deen Morsy Lymphocytes Can Play The Trojan-Horse Role in Polyoma BKV Infection Liang Wei The MicroRNA miR-182 Alters CD4+ T Cell Responses Post-Transplant Sharmila Ramessur The Role of Spleen Tyrosine Kinase in Acute Renal Allograft Rejection in the Rat Carolina Moore Clonal Composition and Specificity of Graft Infiltrating B Cells in Human Cardiac Allograft Vasculopathy Fadi Issa Evaluation and Optimisation of Non-Autologous Human Regulatory T Cell Therapy for Transplantation Seiichi Shimizu Association ofFc-gamma Receptor Gene Polymorphisms With Susceptibility to Bloodstream Infections After Liver Transplantation Masaaki Zaitsu Anti-CD28 Antagonism Using a Monovalent Fab Antibody for the Prolongation of Human Skin Allograft Survival Toshihito Hirai A Novel Approach Inducing Transplant Tolerance By Activated Invariant Natural Killer T Cells With Co Stimulatory Blockade Katrien De Vusser Intrarenal Telomere Length and Intrarenal Arteriosclerosis in Pretransplant Kidney Biopsies Silke Roedder A 17 Gene Blood Assay (kSORT) for Diagnosis and Prediction of Acute Renal Transplant Rejection: Results of the Multicenter AART Study Karolina M. Burghardt Proposed Listing Indications for Pediatric Intestinal Transplant in the New Era of Specialized Care for Intestinal Failure Goutham Kumar Predictors For Better Graft Survival After Intestinal and Multivisceral Transplantation Yuk Man (Kevin) Lei The Microbiota Promotes Skin Allograft Rejection Yanbao Xiong Treg Require Transcription Factor T-bet to Traffic to Draining Lymph Nodes and Prolong Islet Allograft Survival S. Keshwani Pre-Transplant T-Cell Subtype Assessment as a Predictive Tool for CMV Viremia After Transplant Nissreen Elfadawy The Clinical Relevance ofHLA Cw, DQ and DP Mismatches Among The Zero HLA A, B and DR Mismatched Deceased Donor (DD) Kidney Transplant Population Esme Dijke Pediatric Thymic Tissue as a Novel Source for the Expansion of Stable Regulatory T Cells for Cellular Therapy Aunemarie Weissenbacher VCA at Innsbruck Medical University - An Update 14 Years After the First Hand Transplantation Angelo Alberto Leto Barone Either Abatacept or Belatacept in Combination With Donor Bone Marrow Infusion Induces Immune Tolerance Across a Full MHC Barrier in a Translational Large Animal Vascularized Composite Allotransplantation Model Jorge Roque Espinosa CD57+CD4 T Cells and Belatacept Resistant Rejection Makoto Tonsho Successful Tolerance Induction of Lung Allografts in Non-Human Primates Shruti D. Dave Mesenchymal Stem Cells Induced In Vitro Generation of Antigen Specific Regulatory T-Cells Containing CD4+CD8+ Population: A Cell-Based Therapy To Promote Transplantation Tolerance

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc. Esmé Dijke, Canada Expansion of Highly Suppressive FOXP3+ Regulatory T Cells from Pediatric Thymic Tissue Vivek Kute, India Novel Strategy for Tolerance Induction in Living Donor Renal Transplantation Gisele Meinerz, Brazil Increasing Incidence of Tuberculosis after Renal Transplantation in a Brazilian Center Miwa Morita, USA Liver Stromal Cells Contribute to Liver Transplant Tolerance: Involved Cellular and Molecular Mechanisms Nicolas Poirier, France Preclinical Evaluation of FR104, An Antagonist Anti-CD28 Monovalent Fab’antibody, in DTH and Kidney Transplant Primates Models Thomas Rogerson, Australia Tests for Latent Tuberculosis in Potential Transplant Recipients: A Systematic Review Moritz Schmelzle, USA Increased Plasma Levels of CD133+ Microparticles Bearing Ectonucleotidases Are Noted in Acute Liver Failure in Patients and in Experimental Mouse Models Tina Schmidt, Germany Comparative Analysis of Assays for Detection of Cellular Immunity Towards CMV and M. Tuberculosis in Samples from Deceased Donors Adnan Sharif, United Kingdom One-Year Biopsy Data of Antibody-Incompatible Kidney Transplantation and Correlation with Medium-to-Long Term Risk of Allograft Loss – a Prospective Analysis Simo Syrjälä, Finland Ang1 Reduces Ischemia-Reperfusion Injury–Induced Microvascular Dysfunction and Chronic Rejection in Rat Cardiac Allografts Supported through an unrestricted educational grand from: 

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc. Cheguevara Afaneh, USA Differential regulation of positive or negative costimulatory molecules during acute rejection of human renal allografts Russell Hodgson, Australia Prolonged xenograft survival induced by ICOS-IG Is associated with increased Foxp3+ cells Faisal Khan, Canada Genomic instability after allogeneic hematopoietic cell transplantation is frequent in oral mucosa, particularly in patients with a history of chronic graft-vs-host disease, and rare in nasal mucosa Li Li, USA A highly specific novel 3 gene-set can non-invasively predict operational renal allograft tolerance Luiz Lisboa, Canada In vivo viral microRNA profiling in a large cohort of transplant patients with CMV disease Kate Markey, Australia GVHD-associated immune suppression is the result of an intrinsic defect in MHC class II antigen presentation within donor DC Susumu Shibasaki, Japan A single infusion of the ex-vivo generated immunoregulatory dendritic cells under a novel agent, NK026680 markedly prolongs cardiac allograft survival Kazuaki Tokodai, Japan Interruption of a cross-talk between the complement and coagulation cascades improves early outcomes after intraportal islet transplantation Hanna Trydzenskaya, Germany New protocol of BKV-specific T cell analysis allows for improved assessment of phenotypic and functional characteristics of BKV-specific immunity Laura Wozniak, USA Validation of a transcriptional profile of tolerance in pediatric liver transplant recipients Supported through an unrestricted educational grand from: 

TTS • Genzyme Award for Innovation in Surgery and Technology Sheung-Tat Fan, Hong Kong TTS • Genzyme Award for Education and Training in Transplantation Marti Manyalich, Spain TTS • Novartis Award for Outstanding Investigator Driven Clinical Trial  Rutger Ploeg, The Netherlands TTS • Novartis Award for Outstanding Contribution to the Evidence Base for Transplantation Herwig-Ulf Meier-Kriesche, USA TTS • Roche Award for Outstanding Achievement Transplantation Science (Basic)  Jean-Paul Soulillou, France TTS • Roche Award for Outstanding Achievement Transplantation Science (Clinical)       Brian Nankivell, Australia TTS • Roche Award for Excellence in Translational Science        James Southard, USA TTS • Roche Award for Worldwide Impact in Transplantation Rafael Matesanz, Spain TTS • Roche Award for Transplant Infectious Disease     Jay A. Fishman, USA

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc. since 1994. The recipients in 2006 during the 1st World Transplant Congress: Ran Tao LIGATION OF BTLA ON EFFECTOR T CELLS BY HVEM EXPRESSED BY REGULATORY T CELLS (TREGS) CONTRAOLS THE SUPPRESSIVE FUNCTIONS OF TREGS IN VITRO AND IN VIVO Kerem H. Bortecen LOCAL ADMINISTRATION OF IN VIVO GENERATED TREG PREVENT THE REJECTION OF ISLET ALLOGRAFTS Gang Feng EX VIVO GENERATION OF REGULATORY T CELLS THAT PREVENT SKIN AND ISLET ALLOGRAFT REJECTION: A NOVEL ROLE FOR IFN-T. Kerem H. Bortecen LOCAL ADMINISTRATION OF IN VIVO GENERATED TREG PREVENT THE REJECTION OF ISLET ALLOGRAFTS Martin Bodingbauer PROPHYLACTIC BISPHOSPHONATE TREATMENT PREVENTS BONE FRACTURES AFTER LIVER TRANSPLANTATION Amy M. Dowden BONE MORPHOGENETIC PROTEIN 4 (BMP-4) PROMOTES IN VIVO DIFFERENTIATION OF EMBRYONIC STEM CELLS (ESC) INTO LYMPHOID AND MYELOID HEMATOPOIETIC CELLS Shin Itakura MESENCHYMAL STEM CELLS FACILITATE INDUCTION OF MIXED CHIMERISM AND ISLET ALLOGRAFT TOLERANCE WITHOUT GVHD IN THE RAT Matthew J. Vitalone EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) IN CHRONIC ALLOGRAFT NEPHROPATHY (CAN) Jose Caballero-Corbalan NO BENEFICIAL EFFECT OF THE TWO LAYER METHOD (PFC-UW) COMPARED WITH TRANSPORTATION IN UW ALONE ON THE OUTCOME OF HUMAN ISLET ISOLATION AND TRANSPLANTATION: A REPORT ON 214 HUMAN PANCREASES Iris Lee RETROVIRALLY-TRANSDUCED FOXP3+T CELLS PROMOTE PERMANENT SURVIVAL OF FULLY MHC-MISMATCHED CARDIAC ALLOGRAFTS IN IMMUNOCOMPETENT HOSTS Qiquan Sun C4D-POSITIVE ACUTE REJECTION AT DIFFERENT TIME PERIODS AFTER RENAL TRANSPLANTATION: DIFFERENT CLINICO-HISTOPATHOLOGICAL MANIFESTATIONS REQUIRE DIFFERENT TREATMENT STRATEGIES Supported through an unrestricted educational grand from: 

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. The award has been made possible by the generous support of Astellas Pharma Inc. Koji Yazawa, BOSTON, MA , UNITED STATES NEITHER COMPLEMENT INHIBITION NOR DEPLETION OF NATURAL ANTIBODY IS REQUIRED TO AVOID HYPERACUTE OR ACCELERATED ACUTE REJECTION FOLLOW-ING GALT-KO PIG-TO-BABOON RENAL TRANSPLANTATION Tun Jie, MINNEAPOLIS, UNITED STATES PANCREATIC ISLET XENOTRANSPLANTS RESTORE NORMOGLYCEMIA AND INSULIN INDEPENDENCE IN IMMUNOSUPPRESSED NON-HUMAN PRIMATES Svjetlan Boskovic, BOSTON, MA, UNITED STATES LONG TERM (>5 YEARS) OBSERVATIONS IN RENAL ALLOGRAFT RECIPIENTS TREATED WITH CHIMERISM-INDUCING NONMYELOABLATIVE REGIMEN WITH CD154 BLOCKADE Michelle Solomon, LA JOLLA, UNITED STATES CONSTITUTIVE EXPRESSION OF SUPPRESSOR OF CYTOKINE SIGNALING-1 (SOCS-1) IN PANCREATIC ISLETS DELAYS ISLET ALLOGRAFT REJECTION Mona Doshi, IOWA CITY, IA, UNITED STATES SHORT AND LONG TERM OUTCOME OF LIVER TRANSPLANTS FROM DONORS DECEASED AFTER CARDIAC DEATH (DCD) Angela Webster, WESTMEAD, NSW, AUSTRALIA INCIDENCE, RISK AND PREDICTORS OF CANCER AFTER RENAL TRANSPLANTATION; ANANALYSIS OF ANZDATA, THE AUSTRALIA AND NEW ZEALAND DIALYSIS AND TRANSPLANT REGISTRY Maren Ruhnke, KIEL, GERMANY NORMALIZATION OF BLOOD GLUCOSE BY HUMAN MONOCYTE-DERIVED PANCREATIC ISLET-LIKE||CELLS IN STREPTOZOTOZIN DIABETIC MICE||-PERSPECTIVES FOR AUTOLOGOUS CELL THERAPY Hao Wang, LONDON, CANADA INHIBITION OF TERMINAL COMPLEMENT WITH A FUNCTIONALLY BLOCKING ANTI-C5 MONOCLONAL ANTIBODY PREVENTS ACUTE HUMORAL REJECTION AND ACCELERATED HUMORAL REJECTION IN A MOUSE CARDIAC ALLOGRAFT TRANSPLANTATION MODEL Constantino Fondevila, LOS ANGELES, UNITED STATES CYCLIC RGD PEPTIDES WITH HIGH AFFINITY FOR ALPHA5BETA1 INTEGRIN INHIBIT MACROPHAGE RECRUITMENT IN STEATOTIC LIVER ISCHEMIA/REPERFUSION INJURY Robert Öllinger, INNSBRUCK, AUSTRIA BILIRUBIN SUPPRESSES NEOINTIMA FORMATION BY INTERACTING WITH THE RETINOBLASTOMA TUMOR SUPPRESSOR PROTEIN PATHWAY Cecile Braudeau, NANTES, FRANCE BLOOD CD25+CD4+ T CELLS PHENOTYPE AND REGULATION ASSOCIATED MOLECULES IN "OPERATIONALLY TOLERANT” VERSUS CHRONIC REJECTION HUMAN KIDNEY RECIPIENTS Supported through an unrestricted educational grand from: 

International Transplantation Science Mentee-Mentor Awards

2020 INTERNATIONAL TRANSPLANTATION SCIENCE MENTEE-MENTOR AWARDS

THE TRANSPLANTATION SOCIETY (TTS), ALONG WITH COLLABORATION OF NATIONAL AND INTERNATIONAL SOCIETIES, ACKNOWLEDGES THE CONTRIBUTION OF BASIC SCIENCE TO THE FIELD OF TRANSPLANTATION.

CONFIRMED SUPPORTING SOCIETIES:

• ASHI

  

• AST

  

• CST

  

• ESOT

  

• ILTS

  

• IRTA

  

• ISOT

  

• JST

  

• MESOT

  

• SMT

  

• NTV

  

• SAT

  

• SET

  

• SET

  

• SMDT

  

• STALyC

  

• KST

  

• TDTD

  

• TTS

  

• TSANZ

  

• 2018

  

  THE TRANSPLANTATION SOCIETY (TTS), ALONG WITH COLLABORATION OF NATIONAL AND INTERNATIONAL SOCIETIES, ACKNOWLEDGES THE CONTRIBUTION OF BASIC SCIENCE TO THE FIELD OF TRANSPLANTATION

  

  The Transplantation Society celebrates the contributions of basic science to the field of transplantation with the International Transplantation Science Mentee-Mentor Travel Awards by recognizing the efforts of scientists who have advanced our understanding of transplant science and fostered the development of the young investigators who will be the future leaders in our field.

  TTS-CST International Transplantation Science Mentee-Mentor Awards

  Mentee: Minal Borkar-Tripathi, Canada	Mentor: Lee Anne Tibbles, Canada
  Mentee: Ibrahim Adam, Canada	Mentor: Lori West, Canada
  Mentee: Nicholas Dawson, Canada	Mentor: Megan Levings, Canada
  Mentee: Avery Lam, Canada	Mentor: Megan Levings, Canada

  TTS-TSANZ International Transplantation Science Mentee-Mentor Awards

  Mentee: Hong Chee Chew, Australia	Mentor: Peter MacDonald, Australia
  Mentee: Sam Adhikary, Australia	Mentor: Debbie Watson, Australia

  TTS-TOND International Transplantation Science Mentee-Mentor Awards

  Mentee: Selin Akad, Turkey

  Mentor: Feride Sahin, Turkey

  TTS-JST International Transplantation Science Mentee-Mentor Awards

  Mentee: Asuka Tanaka, Japan

  Mentor: Yuka Tanaka, Japan

  TTS-ISOT International Transplantation Science Mentee-Mentor Awards

  Mentee: Sonia Mehrotra, India	Mentor: Raj Kumar Sharma, India
  Mentee: Mohan Patel, India	Mentor: Manoj Gumber, India
  Mentee: Sahil Bagai, India	Mentor: Manish Rathi, India
  Mentee: Manish Balwani, India	Mentor: Pankaj Shah, India
  Mentee: Akhilesh Kumar Jaiswal, India	Mentor: Narayan Prasad, India

  TTS-International Transplantation Science Mentee-Mentor Awards

  Mentee: Jianing Fu, United States	Mentor: Megan Sykes, United States
  Mentee: Wai Ho Oscar Yeung, Hong Kong	Mentor: Nancy Kwan Man, Hong Kong
  Mentor: Gabriel Gondolesi, Argentina	Mentee: Melisa Pucci Molineris, Argentina
  Mentee: Elisa Montanari, Switzerland	Mentor: Léo Hans Bühler, Switzerland
  Mentee: Ahmer Hameed, Australia	Mentor: Wayne Hawthorne, Australia

  TTS-SET International Transplantation Science Mentee-Mentor Awards

  Mentee: Patricia Conde -San Román, Spain	Mentor: Jordi Ochando, Spain
  Mentee: María García-Conde Delgado, Spain	Mentor: Iago Justo, Spain
  Mentee: Oana Anisa Nutu, Spain	Mentor: Iago Justo, Spain

  TTS-NTV International Transplantation Science Mentee-Mentor Awards

  Mentee: Jesus M. Sierra Parraga, Netherlands

  Mentor: Martin Hoogduijn, Netherlands

• 2017

  TTS/ISOT AWARDS
  These awards were made possible with the contribution of the Indian Society of Organ Transplantation.

  Shweta Tyagi, India – Mentee / Uma Kanga, India – Mentor
  EXPRESSION OF SHLA-G IDENTIFIES FAVORABLE OUTCOME IN RENAL TRANSPLANT RECIPIENTS

  Sahil Bagai, India – Mentee / Manish Rathi, India – Mentor
  CORRELATION OF PRETRANSPLANT GLUCOSE METABOLISM WITH THE DEVELOPMENT OF NEW ONSET DIABETES AFTER RENAL TRANSPLANTATION

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  TTS/JST AWARDS
  These awards were made possible with the contribution of the Japan Society for Transplantation.

  Nobuki Ishida, Japan – Mentee / Kohei Ishiyama, Japan – Mentor
  SUPPRESSING LIVER NATURAL KILLER CELLS ACTIVATION BY COTRANSPLANTATION OF PREACTIVATED MESENCHYMAL STEM CELLS CONTRIBUTES TO IMPROVEMENT OF ISLET GRAFT SURVIVAL

  Masakatsu Kaneshiro, Japan – Mentee / Atsushi Yoshizawa, Japan – Mentor
  ANALYSIS OF HUMAN LEUCOCYTE ANTIGEN CLASS II EXPRESSION IN GRAFT LIVER TISSUE; DONOR SPECIFIC ANTIBODIES AND GRAFT LIVER FIBROSIS

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  TTS/NTV AWARDS
  This award was made possible with the contribution of the Nederlandse Transplantatie Vereniging.

  Fleur Peters, The Netherlands – Mentee / Karin Boer, The Netherlands – Mentor
  IDENTIFICATION OF KIDNEY TRANSPLANT PATIENTS AT RISK FOR SKIN CANCER BY DIFFERENTIALLY METHYLATED REGIONS IN T CELLS
  

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  TTS/SET AWARDS

  This award was made possible with the contribution of the Sociedad de Española Trasplante

  Rebeca Arroyo-Hornero, UK – Mentee / Fadi Issa, UK – Mentor

  MODULATION OF CD27/CD70 CO-STIMULATORY PATHWAY MAY ALLOW FOR THE GENERATION OF A MORE POTENT HUMAN REGULATORY T CELL PRODUCT FOR CELL THERAPY

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  TTS/TSANZ AWARDS

  These awards were made possible with the contribution of The Transplantation Society of Australia and New Zealand.

  Mario Leong, Australia – Mentee / Alexandra Sharland, Australia – Mentor
  RECOGNITION OF INTACT DONOR CLASS I BY RECIPIENT CD8+ T CELLS IS REQUIRED FOR TOLERANCE INDUCTION FOLLOWING LIVER-DIRECTED TRANSGENE EXPRESSION

  Paul Wilcox, Australia – Mentee / Bruce M. Hall, Australia – Mentor
  CD8 EXPRESSION INCREASES SUPPRESSIVE ABILITY OF CD4+CD25+TREG AND IS A MARKER OF ANTIGEN-SPECIFICITY

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  TTS AWARDS

  These awards were made possible with the contribution of The Transplantation Society.

  Xiaomeng Hu, USA – Mentee / Sonja Schrepfer, USA - Mentor
  GENERATION OF HYPOIMMUNOGENIC INDUCED PLURIPOTENT STEM CELLS FOR ALLOGENEIC CELL AND TISSUE TRANSPLANTATION

  Timm Heinbokel, USA – Mentee / Stefan G. Tullius, USA – Mentor
  A SHIFTING BALANCE: INNATE IMMUNITY IMPACTS CHARACTERISTICS AND SPECIFICITY OF ALLOIMMUNE RESPONSES IN AGING.

  Yoshihiro Ono, USA – Mentee / Angus Thomson, USA – Mentor
  GRAFT-INFILTRATING PD-L1HI CROSS-DRESSED DENDRITIC CELLS SUBVERT DONOR-REACTIVE T CELL RESPONSES IN MOUSE LIVER TRANSPLANT TOLERANCE.

  Gaelen Dwyer, USA – Mentee / Heth Turnquist, USA – Mentor
  THE “TYPE 2” CYTOKINE, INTERLUKIN-33, GENERATES POTENT

• 2016

  The Transplantation Society (TTS) along with the collaboration of its Affiliated Societies celebrates the contributions of basic science to the field of transplantation with the International Transplantation Science Mentee-Mentor Awards by recognizing the efforts of basic scientists who have advanced our understanding of transplant science/immunobiology and/or treatment of transplant recipients, and the young investigators who will be the future leaders in transplantation.

  The Awards were given on Sunday, August 21, during the International Transplantation Science Mentee-Mentor Networking Event held from 18:30 to 19:30 in the Hong Kong Convention and Exhibition Center.

  TTS Awards

  • AMP-activated protein kinase attenuated marginal liver graft injury via promoting mitochondrial biogenesis and respiratory function
    Mentee: Jiang Liu, Hong Kong
    Mentor: Chung Mau Lo, Hong Kong
  • CD45RA identifies TSDR demethylated regulatory T cells with a stable phenotype and suppressive cytokine profile
    Mentee: Rebeca Arroyo Hornero, United Kingdom
    Mentor: Kathryn Wood, United Kingdom
  • Effect of epigenetic modifications in graft kidneys progressing to chronic allograft dysfunction
    Mentee: Sai Vineela Bontha, United States
    Mentor: Valeria Mas, United States
  • The clinical significance and potential therapeutic role of GPx3 in tumor recurrence after liver transplantation
    Mentee: Xiang Qi, Hong Kong
    Mentor: Nancy Kwan Man, Hong Kong
  • Vascular sequestration of donor-specific antibodies protects allogeneic islets from humoral rejection
    Mentee: Chien-Chia Chen, France
    Mentor: Olivier Thaunat, France
  • Human anti thrombotic genes do not obviate the need for anticoagulation in aiding long term xenograft survival
    Mentee: Joshua Chan, United States
    Mentor: Muhammad Mohiuddin, United States

  TTS - CST Award

  • Prospective treatment and novel biomarkers of BK polyomavirus associated nephropathy
    Mentee: Minal Borkar, Canada
    Mentor: Lori J. West, Canada

  TTS - DTG Awards

  • Cell-free mitochondrial DNA activates DCs in an age-dependent fashion and compromises the survival of older grafts
    Mentee: Midas Seyda, Germany
    Mentor: Stefan G. Tullius, United States
  • Metabolites associated with bariatric surgery reverse accelerated rejection and augmented alloimmunity in obese allograft recipients
    Mentee: Markus Quante, United States
    Mentor: Stefan G. Tullius, United States

  TTS - ISOT Awards

  • Impact of single Centre kidney paired donation transplantation to increase donor pool in India
    Mentee: Vivek Kute, India
    Mentor: Pankaj R. Shah, India
  • Imbalance of T helper 17 cells and T regulatory cells is associated with chronic active antibody mediated rejection in renal allograft recipients
    Mentee: Brijesh Yadav, India
    Mentor: Narayan Prasad, India
  • Peripheral NK-cell repertoire distribution in chronic allograft dysfunction after renal transplantation Sailaja
    Mentee: Kesiraju, India
    Mentor: Sahariah Sarbeshwar, India
  • Ultra-high resolution non-contrast imaging for chronic rejection monitoring and procedural planning in reconstructive transplantation
    Mentee: Shailesh Raval, India
    Mentor: Vijay Gorantla, India
  • Development of de-novo donor specific antibody (DSA) and vitamin D status after renal transplantation
    Mentee: Sonia Mehotra, India
    Mentor: RajKumar Sharma, India

  TTS - JST Awards

  • Clinical and immunological significance of controlling portal vein pressure in living donor liver transplantation
    Mentee: Kazuhiro Taguchi , Japan
    Mentor: Takashi Onoe, Japan
  • Systemic therapy of regulatory dendritic cells derived form induced pluripotent stem cells allows allogeneic cardiac grafts acceptance
    Mentee: Songjie Cai, Japan
    Mentor: Shiro Takahara, Japan
  • Various pathogenic microbes induce CNI- resistance in B-cells responding to blood group antigens through TLR–MyD88 pathway
    Mentee: Hiroshi Sakai, Japan
    Mentor: Yuka Tanaka, Japan

  TTS - NTV Award

  • Belatacept fails to inhibit donor-reactive Tfh-B cell interaction, but favors a regulatory transitional B cell profile over tacrolimus
    Mentee: Gretchen de Graav, Netherlands
    Mentor: Carla Baan, Netherlands

  TTS - SFT Award

  • Interleukin-34 is a Treg-specific cytokine and mediates transplant tolerance
    Mentee: Séverine Bézie, France
    Mentor: Carole Guillonneau, France

  TTS - SMT Awards

  • Pre-transplant AT1Rabs are associated with acute rejection in 2-haplotypes kidney transplant recipients
    Mentee: José Manuel Arreola Guerra, Mexico
    Mentor: Luis Eduardo Morales Buenrostro, Mexico

  TTS - TSANZ Awards

  • Dendritic cell phenotype and function modification with targeted porous silicon nanoparticles
    Mentee: Sebastian Olivier Stead, Australia
    Mentor: Patrick Coates, Australia
  • Surface modification of porcine aortic endothelial cells with Corline Heparin Conjugate (CHC) protects against xenogeneic thrombosis and inflammation
    Mentee: Anjan Bongoni, Australia
    Mentor: Peter Cowan, Australia
  • Risky organs: trends in comorbidities among potential and actual Australian organ donors in New South Wales
    Mentee: Imogen Thomson, Australia
    Mentor: Angela C. Webster, Australia
  • Disruption of CD8-coreceptor binding abrogates tolerance induction via liver- directed expression of donor MHC class I
    Mentee: Moumita Paul-Heng, Australia
    Mentor: Alexandra Sharland, Australia

  

  

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• 2015

  TTS Awards

  • Rapamycin and retinoic acid downregulate the methylation of FoxP3 after restimulation in human Treg derived from naïve T cells
    Mentee: Enzo Candia, Chile
    Mentor: Juan Alberto Fierro Correa, Chile
  • TLR4/CXCL10/CXCR3 signaling mobilized regulatory T cells promote liver tumor recurrence after transplantation
    Mentee: Chang-Xian Li, China
    Mentor: Nancy Kwan Man, China
  • Endogenous graft-specific T cell populations exhibit distinct TCR Avidity profiles during acute rejection and tolerance
    Mentee: Michelle Miller, United States
    Mentor: Maria-Luisa Alegre, United States
  • The effects of valsartan on klotho expression and oxidative stress in preventing of calcinurine inhibitor nephropathy
    Mentee: Sina Raeisi, Iran
    Mentor: Hassan Argania, Iran
  • Prolonged Survival of Porcine Skin on Baboons following Administration of Porcine Cells Expressing Human CD47
    Mentee: Aseda Tena, United States
    Mentor: David Sachs, Unites States
  • Delayed CTLA-4Ig treatment of established acute allograft rejection successfully abrogates ongoing B cell responses
    Mentee: James Young, United States
    Mentor: Anita Chong, United States

  TTS - CST Awards

  • Potent Suppression of allogeneic and xenogeneic immunity by cryopreserved regulatory T cells (Tregs) isolated and expanded from human thymus
    Mentee: Esme Dijke, Canada
    Mentor: Lori West, Canada
  • Tailoring Homing Capacity of Thymic regulatory T Cells by Expansion in Cytokline-enriched culture conditions
    Mentee: Romy Hoeppli, Canada
    Mentor: Megan Levings, Canada

  TTS - DTG Awards

  • Ciclosporine A, but not rapamycin, downregulates T-bet in CD8 T cells leading to a diminished anti-tumor activity against B16 melanoma in mice
    Mentee: Philip Renner, Germany
    Mentor: Edward Geissler, Germany

  TTS - ESOT Awards

  • Ex vivo generation of alloantigen-specific T regulatory cells using selective T-cell co-stimulation blockade
    Mentee: Masaaki Watanabe, Sweden
    Mentor: Bo-Goran Ericzon, Sweden

  TTS - JST Awards

  • Bacterial pathogens provoke B cells responding to blood group A-antigens to be resistant to calcineurin inhibitors through TLR - MyD88 pathway
    Mentee: Hiroshi Sakai, Japan
    Mentor: Yuka Tanaka, Japan
  • Propagated NK cells from human pluripotent stem cells exert vigorous cytotoxicity against HCC and inhibit HCV replication
    Mentee: Selichi Shimizu, Japan
    Mentor: Yuka Tanaka, Japan

  TTS - TSANZ Awards

  • P2X7 blockade reduces interferon gamma in a humanised mouse model of graft-versus-host disease
    Mentee: Nicholas Geraghty, Australia
    Mentor: Debbie Watson, Australia
  • Autophagy-dependent TIGIT positive Helios positive regulatory T cells are critical for controlling GVHD after allogeneic stem cell transplantation
    Mentee: Laetitia Le Texier, Australia
    Mentor: Kelli P. MacDonald, Australia
  • Characterisation of the immunomodulatory action of a unique anti-CXCR3 monoclonal antibody exploiting a conserved human and murine epitope for transplantation
    Mentee: Suzanna Pilgrim, Australia
    Mentor: Shane Grey, Australia
  • Microarray gene profile study of immunosuppressive interleukin-17A preactivated human Mesenchymal Stem Cells
    Mentee: Kisha N. Sivanathan, Australia
    Mentor: Patrick T. Coates, Australia
  • Genetic polymorphisms in donor tissue determinetransplant outcomes
    Mentee: Nathan Zammit, Australia
    Mentor: Shane Grey, Australia

  

  

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• 2014

  2014 INTERNATIONAL TRANSPLANTATION SCIENCE MENTEE–MENTOR AWARDS

  TTS Awards

  • Mentee: Charles Colin Brinkman, United States
    Mentor: Dr. Jonathan Bromberg, Unites States
  • Mentee: Estafania Nova Lamperti, United Kingdom
    Mentor: Dr. Maria Hernandez-Fuentes, United Kingdom
  • Mentee: Yuk Man (Kevin) Lei, United States
    Mentor: Dr. Maria-Luisa Alegre, Unites States
  • Mentee: Niloufar Safinia, United Kingdom
    Mentor: Prof. Giovanna Lombbardi, United Kingdom

  TTS - CST Awards

  • Mentee: Shanil Keshwani, Canada
    Mentor: Dr. Atul Humar, Canada
  • Mentee: Minh-Tri Nguyen, Canada
    Mentor: Dr. Steven Paraskevas, Canada

  TTS - DTG Awards

  • Mentee: Markus Quante, United States
    Mentor: Prof. Stefan Tullius, United States
  • Mentee: Paloma Riquelme, Germany
    Mentor: Dr. James Alexander Hutchinson, Germany

  TTS - ESOT Awards

  • Mentee: Fadi Issa, United Kingdom
    Mentor: Prof. Kathryn Wood

  TTS - ILTS Awards

  • Mentee: Sergio Duarte, United States
    Mentor: Prof. Ana J. Coito, United States
  • Mentee: Lung-Yi Lee, United States
    Mentor: Prof. Jon Odorico, United States
  • Mentee: Chang-Xian Li, China
    Mentor: Prof. Nancy Kwan Man, China
  • Mentee: Shinichiro Yokota, United States
    Mentor: Dr. Angus W. Thomson, United States

  TTS - ISHLT Awards

  • Mentee: Carolina Moore, United States
    Mentor: Dr. Joren Madsen, United States

  TTS - JST Awards

  • Mentee: Toshihiro Hirai, Japan
    Mentor: Prof. Kazunari Tanabe, Japan
  • Mentee: Taigo Kato, Japan
    Mentor: Dr. Masayoshi Okumi, Japan

  TTS - SFT Awards

  • Mentee: Sylvain Le Pape, France
    Mentor: Dr. Raphael Thullier, France
  • Mentee: Elodie Picarda, France
    Mentor: Dr. Carole Guilonneau, France

  TTS - TSANZ Awards

  • Mentee: Kylie Alexander, Australia
    Mentor: Dr. Kelli MacDonald, Australia
  • Mentee: Kisha Sivanathan, Australia
    Mentor: Prof. Patrick Coates, Australia

  

  

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• 2013

  The Transplantation Society (TTS), along with the collaboration of National Societies acknowledge the contributions of basic science to the field of Transplantation. The International Basic Science Mentee-Mentor awards recognized the efforts of established basic scientists, who have advanced our understanding of transplant science/immunobiology and /or treatment of transplant recipients, and the mentorship of new young investigators who have the potential to contribute to the basic science of transplantation. The International Basic Science Mentee-Mentor award recipients for the BSM 2013 are listed below.

  TTS Awards

  Mentee	Mentor	Abstract Title
  Abdelrarik, Heba, Egypt	Joosten, Irma	Human Platelet Lysate increases MSC proliferation on the expense of its Haematopoietic progenitor cell support
  Candia, Enzo, Chile	Fierro, Alberto	Differential modulation of homing receptors in polyclonal human Treg generated ex vivo
  Hock, Karin, Austria	Wekerle, Thomas	Donor CD4 T cells trigger costimulation blockade-resistant donor bone marrow rejection through bystander activation requiring interleukin 6
  Oberhuber, Rupert, Austria	Tullius, Stefan	Intracardiac CD11c+ dendritic cells trigger the more potent IL-17 mediated immune response after transplanting older cardiac allografts
  Yang, Cheng, China	Yang, Bin	Serum Stabilized Naked Caspase-3 siRNA Protects Auto-transplant Kidneys in a Porcine Model
  Zaitsu, Masaaki, United Kingdom	Wood, Kathryn	Prolongation of human skin allograft survival with FR104, an antagonistic antiCD28 monovalent Fab antibody

  TTS - CST Awards

  Mentee	Mentor	Abstract Title
  Borkar, Minal, Canada	Tibbles, Lee Anne	BK polyoma virus epigenetically regulates transcription of epithelial markers in proximal tubular cells: Model for fibrosis in BK infected transplant recipients
  White, Christopher, Canada	Freed, Darren H.	A donor whole blood-based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion

  TTS - DTG Awards

  Mentee	Mentor	Abstract Title
  Sabet-Baktach, Manije, Germany	Geissler, Edward K.	Th2 Responses mediate Allograft Rejection in RORgammat and T-bet DoubleDeficiency in Mice

  TTS - ILTS Awards

  Mentee	Mentor	Abstract Title
  Li, Chang Xian, China	Man, Kwan	The knockout of telomere-independent Rap1 attenuates liver graft injury by suppressing macrophage activation
  Takaoka, Yuki, Taiwan	Nakano, Toshiaki	Autoimmunity vs. alloimmunity: its involvement in liver transplant tolerogenicity
  Yoshida, Osamu, United States	Thomson, Angus	CD39 expression by hepatic myeloid dendritic cells attenuates their proinflammatory activity and liver transplant ischemia-reperfusion injury

  TTS - ISHLT Awards

  Mentee	Mentor	Abstract Title
  Dijke, Esme, Canada	West, Lori J.	CD25+FOXP3+ regulatory T cells (Tregs) isolated and expanded from pediatric thymus maintain stable phenotype and function under inflammatory conditions
  Guihaire, Julien, Germany	Schrepfer, Sonja	Over-expression of S100A4 protein is T cells-mediated in a humanized model of chronic Obliterative Airway Disease
  Pilat, Nina, Austria	Wekerle, Thomas	Mechanisms of Treg therapy in a murine mixed chimerism model

  TTS - SFT Awards

  Mentee	Mentor	Abstract Title
  Durand, Justine, France	Chiffoleau, Elise	Characterization of regulatory B cells in an allograft rodent model, able to transfer tolerance
  Yap, Michelle, France	Degauque, Nicolas	An increase of highly differentiated TEMRA CD8 T cells with potent effector function in kidney transplant recipients with stable graft function revealed patients with at-risk of long-term graft function

  TTS - JST Awards

  Mentee	Mentor	Abstract Title
  Abe, Tomoyuki, Japan	Tanaka, Yuka	The CD47-SIRP-α signaling blockade accelerates macrophage phagocytic activity against hepatocellular carcinoma even under immunosuppressive conditions
  Cai, Songjie, Japan	Takahara, Shiro	Silencing CD40 gene to induce transplantation tolerance using a novel siRNA delivery system
  Koshizuka, Yasuyuki, Japan	Yamashita, Kenichiro	Roles of CD40-CD40L costimulatory pathway in pancreatic islet transplantation

  TTS - TSANZ Awards

  Mentee	Mentor	Abstract Title
  Fang, Doreen, Australia	Dwyer, Karen	Follistatin reduces serum activin and attenuates renal ischemia reperfusion injury in mice
  Habib, Miriam, Australia	Sharland, Alexandra	Ischaemia-reperfusion injury propagates tumour growth in a mouse model of hepatocellular carcinoma

• 2012

  The Basic Science Mentee-Mentor award recognizes the efforts of established basic scientists, who have advanced our understanding of transplantation biology and the treatment of transplant recipients, as well as the mentorship of new young investigators who will advance transplantation in the future. We are pleased to announce the partnership between The Transplantation Society (TTS) and 7 National and International Transplantation Societies to support 27 Mentee-Mentor Award recipients for the 24th International Congress of The Transplantation Society. Congratulations to the 2012 Award Recipients!

  TTS Awards

  Mentee	Mentor	Abstract Title
  Liu, Longshan, China	Wang, Changxi	Donor-Derived Mesenchymal Stem Cells Facilitate Minimization of Calcineurin Inhibitors in Kidney Transplant Patients and the Immune Profile Monitoring: A Clinical Pilot Study
  Ortiz, Yaneth, Colombia	Garcia, Luis	Memory Phenotype and Polyfunctional T Cells in Kidney Transplant Patients
  Qi, Xiang, China	Man, Kwan	Acute Phase Graft Injury Promotes Tumor Invasiveness through Down-Regulation of Glutathione Peroxidase 3 (GPx3) after Liver Transplantation
  Skvorak, Kristen, United States	Strom, Stephen	Hepatocyte Transplantation Improves Blood and Brain Phenylalanine and Neurotransmitter Imbalances in a Mouse Model of Phenylketonuria (PKU)
  Yang, Cheng, China	Yang, Bin	Naked Caspase-3 Small Interfering RNA (SiRNA) Was Effective in Cold Preservation of Isolated Porcine Kidneys, but Did not Protect Preserved Kidneys after Auto-Transplantation

  TTS - British Transplantation Society Awards

  Mentee	Mentor	Abstract Title
  Ali, Jason, United Kingdom	Pettigrew, Gavin	Assessment of Longevity of the Direct and Indirect CD4 T Cell Allorecognition Response
  Cole, Jennifer, United Kingdom	Pettigrew, Gavin	Memory CD4+ T Cells that Recognise Additional Mismatched Alloantigen Provide CD40-independent Help for Effector Anti-MHC Class I Alloantibody Responses
  Issa, Fadi, United Kingdom	Wood, Kathryn	Homing of Therapeutic Human Regulatory T Cells to the Allograft Site Enhances Transplant Survival
  Nova Lamperti, Estefania, United Kingdom	Hernandez-Fuentes, Maria	Higher IL10 Production by Transitional B Cells in Tolerant Kidney Transplant Recipients

  TTS - Canadian Society of Transplantation Awards

  Mentee	Mentor	Abstract Title
  Jeyakanthan, Mylvaganam, Canada	West, Lori	T-Cell Dependency of T-Independent (TI) Antigens: Antibody Response to Blood Group A-Antigen Requires CD4 T-Cells and CD40/CD40L Interaction
  Nguyen, Minh-Tri, Canada	Tchervenkov, Jean	Pre-Operative Regulatory T Cell Suppressive Function Correlates with Short-Term Graft Outcome after Kidney Transplantation
  Srivastava, Vikas, Canada	Tibbles, Lee Anne	BK Polyoma Virus Induces Aberrant Methylation of Host Genome to Promote Epithelial Mesenchymal Transition and Fibrosis

  TTS - Deutsche Transplantationsgesellschaft Awards

  Mentee	Mentor	Abstract Title
  Heim, Christian, Germany	Ensminger, Stephan	PHD (Prolyl-Hydroxylase)-Inhibitor Activating Hypoxia-Inducible Transcription Factors (HIFs) Reduces Levels of Transplant Arteriosclerosis in a Murine Aortic Allograft Model
  Hua, Xiaoqin, Germany	Schrepfer, Sonja	Immunobiology of SCNT Derived Embryonic Stem Cells: Pivotal Role of mtDNA in Rejection of Transplanted Stem Cells
  Raschzok, Nathanael, Germany	Sauer, Igor M.	Silica-Based Micron-Sized Iron Oxide Particles for Detection and Loco-Regional Stimulation of Transplanted Liver Cells
  Riquelme, Paloma, Germany	Hutchinson, James	Prolongation of Allograft Survival by Regulatory Macrophages in Mice Is iNOS-Dependent
  von Websky, Martin, Germany	Schaefer, Nico	Reduced Expression of Mucosal Antimicrobial Peptides in the Small Intestine During Acute Rejection after Orthotopic Small Bowel Transplantation

  TTS - European Society for Organ Transplantation Awards

  Mentee	Mentor	Abstract Title
  Petrelli, Alessandra, Italy	Battaglia, Manuela	Efficient Generation of Donor-Specific Tr1 CELLS from Patients on Hemodialysis

  TTS - The Japan Society for Transplantation Awards

  Mentee	Mentor	Abstract Title
  Hotta, Ryuichi, Japan	Tanaka, Yuka	NK Cells Differentiated from Hematopoietic Stem Cells Exert Anti-HCC and Anti-HCV Activities Similar to Those of Peripheral Blood-Propagated NK Cells
  Iwami, Daiki, Japan	Shirasugi, Nozomu	CD8+ Dendritic Cells with Regulatory Function Generated by Intratracheal Delivery of Alloantigen Induces Prolonged Cardiac Allograft Survival
  Tasaki, Masayuki, United States	Yamada, Kazuhiko	Prevention of Early Development of Proteinuria by Rituximab in a Pig to Baboon Thymokidney Model Likely Associated with Modulating Podocyte Function in An SMPDL-3b-Dependent Manner

  TTS - Société Francophone de Transplantation Awards

  Mentee	Mentor	Abstract Title
  Baulier, Edouard, France	Favreau, Frederic	Metabonomic Analysis of Perfusion Solution with NMR: A Potential Tool to Predict Graft Outcome in Deceased after Cardiac Arrest Donor Conditions

  TTS - The Transplantation Society of Australian and New Zealand Awards

  Mentee	Mentor	Abstract Title
  Cunningham, Eithne, Australia	Bishop, G. Alex	Overcoming Naïve and Memory Immune Responses in a Mouse Skin Transplant Model Using High-Level Expression of Donor MHC Antigen in Recipient Livers
  Hope, Christopher M., Australia	Carroll, Robert	Regulatory T Cells and the Development of Cancer Post Renal Transplantation
  Hu, Min, Australia	O’Connell, Philip	A Key Role for Tregs in Renal Allograft Survival: Specific Deletion of Tregs in DEREG Mice Breaks Tolerance in Renal Transplants in the Murine DBA/2 to C57BL/6 Model
  Villanueva, Jeanette, Australia	Grey, Shane	TRAF2 Governs the T Cell Alloimmune Response
  Zammit, Nathan, Australia	Grey, Shane	Improved Survival Characteristics of An Inflammatory Suppressed Allograft

• 2011

  The Transplantation Society (TTS), along with the collaboration of National Societies acknowledge the contributions of basic science to the field of Transplantation. The Basic Science Mentee/Mentor award recognizes the efforts of established basic scientists, who have advanced our understanding of transplant science/immunobiology and/or treatment of transplant recipients, and the mentorship of new young investigators who have the potential to contribute to the basic science of transplantation. The Mentee-Mentor Award recipients for the BSS 2011 are listed below.

  TTS Awards

  Mentee	Mentor	Abstract Title
  Ata, Pinar, Turkey	Tittiz, M. Izzet	Flowcytometric detection of anti-AB antibody titers in blood group O renal recipients with blood group A2 donors
  Hock, Karin, Austria	Wekerle, Thomas	Mechanistic analysis of costimulation blockade-resistant rejection of donor bone marrow triggered by donor T cells
  Li, Changxian, People’s Republic of China	Man, Kwan	Aldose reductase accelerates small-for-size fatty liver graft injury
  Liu, Quan, USA	Zheng, Xin Xiao	Vascularized Bone Marrow Transplantation: A New Approach to Induce Organ Transplant Tolerance
  Moore, Carolina, Chile	Rosemblatt, Mario	Allogeneic Treg generated in vitro with retinoic acid and TGF-β control cytokine production and allograft rejection
  Qi, Xiang, People’s Republic of China	Man, Kwan	Down-regulation of Glutathione peroxidase 3 (GPx3) by acute phase inflammation in small-for-size graft promotes tumor invasiveness after liver transplantation

  TTS - AST Awards

  Mentee	Mentor	Abstract Title
  Bhatt, Sumantha, USA	Valujskikh, Anna	Neutralizing BAFF and APRIL in combination with anti-CD154 Ab treatment and CD8+ T cell depletion induces long term cardiac allograft survival in mice containing memory CD4+ T cells
  Krzystyniak, Adam, USA	Witkowski, Piotr	Coating of human pancreatic islets with CD4+CD25+CD127- T regulatory cells inhibits rejection. A novel immunoprotective approach.
  Zhang, Wensheng, USA	Zheng, Xin Xiao	CTA containing vascularized bone marrow offer the inherent potential for stable mixed chimerism and tolerance.

  TTS - BTS Awards

  Mentee	Mentor	Abstract Title
  Ellis, Jonathan, UK	Inston, Nicholas	Histone Deacetylase Inhibition reveals a potent immunosuppressant effect in an in vitro model of Transplantation

  TTS - CST Awards

  Mentee	Mentor	Abstract Title
  Dijke, Esme, Canada	West, Lori	Impact of thymectomy and heart transplantation on CD4+FOXP3+ T-cell diversity in infants

  TTS - ESOT Awards

  Mentee	Mentor	Abstract Title
  Grohnert, Anja, The Netherlands	Baan, Carla	IL-2-independent induction of novel CD4+CD25+CD127-FOXP3+ T cells by mesenchymal stem cells and natural regulatory T cells
  Riquelme, Paloma, Germany	Geissler, Edward	Mouse Macrophages Driven to a Novel State of Activation Prolong Allograft Survival in Unconditioned, Non-immunosuppressed Recipients
  Sabet-Baktach, Manije, Germany	Schlitt, Hans J.	Cutting-edge model to study the role of RORgT in T17-mediated allograft rejection
  Schmuek, Michael, Germany	Volk, Hans-Dieter	Impaired IL2 signaling promotes CD4-mediated antiviral CD8+ T cell response

  TTS - SFT Awards

  Mentee	Mentor	Abstract Title
  Taflin, Cécile, France	Mooney, Nuala	Human microvascular endothelial cells induce polarization of Th-17 and regulatory-T cell sub-populations under inflammatory conditions

  TTS - JST Awards

  Mentee	Mentor	Abstract Title
  Tazawa, Hirofumi, Japan	Ohdan, Hideki	Pivotal role of invariant NKT cell - B cell interaction in antibody production against transplant-associated carbohydrate epitopes

  TTS - TSANZ Awards

  Mentee	Mentor	Abstract Title
  Cunningham, Eithne, Australia	Bishop, Alex	High level expression of donor MHC in recipient liver promotes mouse skin transplant tolerance
  Habib, Miriam, Australia	Sharland, Alexandra	Systemic overexpression of endogenous secretory RAGE attenuates renal ischaemia-reperfusion injury
  Rogers, Natasha, Australia	Coates, Toby	Amelioration of renal ischemia-reperfusion injury by liposomal delivery of an NFBκB inhibitor to renal tubular epithelial and antigen presenting cells

• 2010

  MENTEE	ABSTRACT TITLE	MENTOR
  Arthur Andakyan, United States	CD4CD25 Positive Mast Cells in Long-Term Surviving Grafts Followed by T-Regulatory Therapy: MC-regs?	Natalya Semiletova
  Sonal Asthana, Canada	The Impact of Sirolimus Based Immunosuppression on Response to Anti-HCV Therapy After Liver Transplantation	Norman Kneteman
  Agata Bartczak, Canada	FGL2 expression induces graft survival in the absence of immunosuppression.	Gary Levy
  Lars Burdorf, United States	Pilot evaluation of anti-GP1b effects on platelet sequestration in an ex vivo xenogeneic pig liver perfusion model	Richard N. Pierson III
  Hong Shiue Chou, United States	In Vivo Evidence: the Role of Complement Component 3 (C3) in Induction of Myeloid-Derived Suppressor Cells (MDSC)	Shiguang Qian
  Pietro Cippà, Switzerland	Bcl-2 inhibition: a new concept to prevent solid allograft rejection	Thomas Fehr
  Marcella Franquesa, Spain	Cell therapy using MSCs and BMDCs in rat kidney transplantation	Immaculada Herrero-Fresneda
  Wei Geng, China	The potential role of early-phase graft injury in induction of late-phase chemoresistance after liver transplantation	Chung-Mau Lo
  Ines Goncalves Harper, United Kingdom	A Novel Mechanism for Alloantibody Production.	Gavin Pettigrew
  Aleishia Harris, United States	Modulation of Cellular MicroRNA by Latent Membrane Protein 1 of Epstein Barr Virus in B Cell Lymphomas Type: Oral Sessions Topic: 06. Complications / e. Malignancy Authors	Olivia  Martinez
  Min Hu, Australia	Allograft Tolerance in Mice with MGMT Chimeric Bone Marrow Engraftment	Stephen  Alexander
  Yanfei Huang, United States	Kidney-derived mesenchymal stem cells modulate dendritic and T cell function to inhibit alloimmune responses and prolong allograft survival	Karl Womer
  Fadi Issa, United Kingdom	Regulatory T cell therapy prolongs human skin allograft survival in humanised mouse model	Kathryn Wood
  Mylvaganam Jeyakanthan, Canada	Is blood group antigen expression on vascular endothelium required for B cell tolerance induction following ABO-incompatible transplant during immunological immaturity?	Lori West
  Gillian Kinnear , United Kingdom	Blockade of OX40 costimulation reduces the alloreactive effector T cell pool and prevents CD8+ T cell mediated skin allograft rejection.	Nicholas Jones
  Zhu Lan, Canada	Suppression of Antidonor Antibody Response by Soluble CD83 Prevents Chronic Renal Allograft Rejection	Hao Wang
  Anlun Ma, Canada	Contribution of regulatory T cells combined with low-dose Sirolimus, but not Tacrolimus, to delay acute rejection of renal allografts in cynomolgus monkeys	Huifang Chen
  Carolina  Moore, Chile	Allogeneic Treg generated in vitro with retinoic acid and TGF-β control cytokine production and allograft rejection.	Mario  Rosemblatt
  Gerhard Mundinger, United States	Chronic rejection in a non-human primate model of facial composite tissue allotransplantation: clinical, pathological, and immunohistochemical characterization	Rolf Barth
  Graeme O'Boyle, United Kingdom	A strategy to inhibit effector T cell infiltration of allograft tissues by stimulation of the chemokine receptor CXCR3	John Kirby
  Nina Pilat, Austria	Administration of polyclonal recipient Tregs leads to mixed chimerism, skin and heart graft tolerance without irradiation	Thomas  Wekerle
  Siddharth Rajakumar, Australia	CD73 deficiency and inhibition protect in kidney ischaemia reperfusion injury (IRI)	Karen Dwyer
  Tim Searcy, Australia	Synergistic Immunomodulation by Immunosuppressive agentsand Human Mesenchymal Stem Cells on T-cell proliferation andDendritic cell maturation	Ravi Krishnan
  Helena Smith-Hurst, Australia	A pathway for Human Islet Protease-Activated Receptors (PARs) in Tissue Factor mediated Immediate Blood Inflammatory Reaction.	Philip O'Connell
  Özlem Tapirdamaz, Netherlands	Detailed kinetics of T-cells with direct allospecificity after liver transplantation: a novel assay	Jaap Kwekkeboom
  Angela Tjon, Netherlands	In vivo immunosuppressive effects of intravenous immunoglobulin on innate and adaptive immune cells involved in allograft rejection	Jaap Kwekkeboom
  Liang Wei, United States	Acute Rejection of Cardiac Allografts results in a Unique Signature of MicroRNAs	Sheri Krams

The Medawar Prize

The Medawar Prize, named after Society co-founder Sir Peter Medawar, is recognized as the world's highest dedicated award for the most outstanding contributions in the field of transplantation. The Medawar Prize has been awarded at each of our Society's biennial Congresses since 1990. The award recognizes the outstanding investigators whose contributions have had such a profound influence on the field of organ transplantation. The Medawar Prize is universally considered to be commensurate with the most outstanding world prizes for scientific achievement. Details & Past Laureates

These awards recognize individuals who have made a major international impact in the field of transplantation. The awards are given out at each International Congress of The Transplantation Society. Details & Past Winners

The Young Investigator Awards are given to recipients who have submitted abstracts to the International Congress of The Transplantation Society and received the highest scores from an international panel of reviewers. Details & Past Winners

The Transplantation Society (TTS), along with collaboration of National and International Societies, acknowledges the contribution of basic science to the field of Transplantation. Details & Past Winners

The Transplantation Science Committee (TSC) of The Transplantation Society (TTS) will award the first two new prestigious annual prizes to the best basic science and translational science papers published in Transplantation. Details & Past Winners

The Transplantation Society provides travel grants for young investigators and for those with financial difficulties who are members of The Transplantation Society. . Details & Past Winners