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Transplantation Science Committee - BEST PAPER in TRANSPLANTATION AWARDS

DEADLINE JUNE 30

The Transplantation Science Committee (TSC) of The Transplantation Society (TTS) announces 2 new prestigious prizes to be awarded annually to the best basic science and translational science published in Transplantation.

Click here​ or download the application form

Transplantation Journal - Featured Article

Submitted by Dr Andrea Schlegel, Editorial Fellow, Transplantation.

Transplant Site Influences the Immune Response After Islet Transplantation: Bone Marrow Versus Liver.
Cantarelli E, Citro A, Pellegrini S, et al.
Transplantation. 2017;101: 1046–1055

Catarelli and coworkers have recently shown that the bone marrow (BM) may represent a valid alternative site for islet infusion. Here, the authors characterized the immune response directed to islet cells transplanted into 2 different sites: the bone marrow (BM) or the liver. The authors used a preclinical mouse model with or without immunosuppression. Mice had been treated with tacrolimus and mycophenolate mofetil, anti-CD3, or a combination of those immunosuppressants. Moreover, the authors tested different histocompatibility differences in addition to a single antigen-mismatched mouse model (C57BL/6 RIP-GP in C57BL/6).

In the absence of immunosuppression, the transplant site did neither impact, kinetics of alloimmune nor antigen-specific memory T cell responses. However, islets infused into the BM appeared less protected from the adaptive immune response when an immunosuppression with anti-CD3 had been applied. Overall, this study raises concerns over the possibility of using the BM as a potential site for islet cell allotransplantation.

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Early Bird Registration Deadline - June 23

New Program Additions and Enhancements!

Program Highlights

• Program-at-a-Glance
• Plenary Speakers
• Invited Speakers
• Hyperimmunized / iABO Pre-Meeting Symposium
• FDA-IXA Symposium
• Sponsored Luncheon Workshops
• Theological Symposium

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Novel molecular approaches to the detection of heart transplant rejection

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The impact of septicemia occurring during hospitalization for renal transplantation procedures on outcomes in adults in United States

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Hemodialysis and idney Transplantation as Predisposing Conditions to Onychomycosis

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